Comiket-themed episodes are common in any anime series dealing with otaku culture (just as the World Series provides the climax for most baseball movies), but Genshiken seems to have best captured the atmosphere of the biannual affair.
I'm reminded of how mundane fan conventions and gatherings tend to be. Despite how absurd such events may appear to outsiders, for those of us "in the loop", much of what happens within the confines of the convention space isn't all that out of the ordinary. Of course, even the toughest American fan would likely be overwhelmed on first attending Comiket. I know I would.
So far, I'm enjoying Genshiken much more than Comic Party. The jokes and references just hit closer to home. Even the little things draw a nod and a laugh.